(Rac)-BMS-986449
Product Sizes
1 mg
£ POA
HY-173630A-1MG
About this Product
- SKU:
- HY-173630A
- Extra Details:
- (R)-BMS-986449 is the racemic mixture of BMS-986449 (HY-173630). BMS-986449 is a CELMoD molecular glue and an IKZF2/IKZF4 degrader. BMS-986449 targets the degradation of transcription factors Helios (IKZF2) and Eos (IKZF4) in regulatory T (Treg) cells. BMS-986449 redirects the E3 ubiquitin ligase Cereblon to induce the degradation of Helios and Eos; reprogramming Treg cells and enhancing antitumor immunity. BMS-986449 is promising for research of advanced solid tumors[1].
- Molecular Weight:
- 396.41
- Purity:
- 99.05
- Research Area:
- Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; stored under nitrogen)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
