Adenosine-3';5'-bisphosphate
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HY-173593-1EACH
About this Product
- SKU:
- HY-173593
- CAS Number:
- 1053-73-2
- Extra Details:
- Adenosine-3';5'-bisphosphate is an exoribonuclease XRN1 inhibitor with an IC50 of 36 nM; a KD of 12 nM; and a KD of 14 nM against human XRN2. Adenosine-3';5'-bisphosphate binds to the bimetallic active site of human XRN1; and also binds potently to human XRN2 via its conserved bimetallic active site. Adenosine-3';5'-bisphosphate can be used in research related to non-small cell lung cancer[1].
- Molecular Weight:
- 427.20
- References:
- [1]Lockbaum GJ, et al. Characterization of exoribonuclease XRN1 as a cancer target and identification of adenosine-3',5'-bisphosphate as a potent enzyme inhibitor. Commun Biol. 2025 Apr 9;8(1):589.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Molecular Biology Reagents: Nucleic Acids
