PD-L1/HDAC3-IN-1
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HY-173558-1EACH
About this Product
- SKU:
- HY-173558
- Extra Details:
- PD-L1/HDAC3-IN-1 (PH3) is a dual PD-L1/HDAC3 Inhibitor with IC50 values of 89.4 nM and 107 nM for PD-1/PD-L1 and HDAC3; respectively. PD-L1/HDAC3-IN-1 induces cell apoptosis and arrests cell cycle at G0/G1 phase. PD-L1/HDAC3-IN-1 shows anticancer activity both in vivo and in vitro[1].
- Molecular Weight:
- 446.58
- References:
- [1]Wang Z, et al. Discovery of Dual PD-L1/HDAC3 Inhibitors for Tumor Immunotherapy. J Med Chem. 2025 Apr 24;68(8):8046-8064.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
