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Proteins and Peptides

PD-1/PD-L1-IN-55

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HY-173464-1EACH
About this Product
SKU:
HY-173464
CAS Number:
3052262-83-3
Extra Details:
PD-1/PD-L1-IN-55 (compound D6) is a potent PD-1/PD-L1 inhibitor with an IC50 of 4.8 nM. PD-1/PD-L1-IN-55 promotes IFN-γ secretion and reduces the proportion of PD-L1 late apoptosis[1].
Molecular Weight:
434.91
References:
[1]Lu T, et al. Design, Synthesis, Evaluation, and SAR of 5-Phenylisoindoline Derivatives, a Potent Class of Small-Molecule Inhibitors Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 (PD-1/PD-L1) Interaction. J Med Chem. 2025 Apr 10;68(7):7291-7312.
Research Area:
Cancer
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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