DOTAGA-FAP-2286-ALB
Product Sizes
50 mg
£ POA
HY-173374-50MG
10 mg
£ POA
HY-173374-10MG
25 mg
£ POA
HY-173374-25MG
1 mg
£ POA
HY-173374-1MG
5 mg
£ POA
HY-173374-5MG
10mM/1mL
£ POA
HY-173374-10MM
About this Product
- SKU:
- HY-173374
- Application:
- Antibody Microarray
- CAS Number:
- 3114056-16-2
- Extra Details:
- DOTAGA-FAP-2286-ALB is a derivative of Rofapitide tetraxetan (HY-147057). DOTAGA-FAP-2286-ALB is a selective fibroblast activation protein (FAP) inhibitor with an IC50 value of 67.5 nM. DOTAGA-FAP-2286-ALB enhances tumor retention via albumin interaction; prolonging blood circulation and improving radiometal complex stability (e.g.; with 111In and 225Ac). DOTAGA-FAP-2286-ALB is promising for research of radionuclide therapy (TRT) of FAP-positive solid tumors[1].
- Molecular Weight:
- 2072.21
- Purity:
- 99.29
- References:
- [1]Saito K, et al. Preclinical Characterization of Novel FAP-2286-Based Radioligand with Albumin Binder for Improved Tumor Retention. ACS Med Chem Lett. 2025 Mar 24;16(4):596-601.
- Research Area:
- Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; stored under nitrogen)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
