2-5A (pentasodium) solution (100mM)
Product Sizes
50 μL
£ POA
HY-173189A-50UL
100 μL
£ POA
HY-173189A-100UL
About this Product
- SKU:
- HY-173189A
- Additional Names:
- 2′;5′-ApApA (pentasodium); 2′;5′-trioligoadenylate (pentasodium); 5'-O-Triphosphoryladenylyl-(2'→5')-adenylyl-(2'→5')-adenosine (pentasodium)
- Extra Details:
- 2-5A (2′;5′-ApApA) pentasodium solution 100 mM is a high-affinity (Ka=0.04 nM) RNase L binder. 2-5A pentasodium solution 100 mM activates the nuclease activity of latent RNase L to cleave single-stranded RNA by inducing conformational changes and dimerization of latent RNase L; thereby mediating critical antiviral responses and enhancing interferon effects. 2-5A pentasodium solution 100 mM not only effectively inhibits Rauscher murine leukemia virus replication; reduces viremia and splenomegaly; but also enhances antileukemic efficacy when combined with amphotericin B and exhibits favorable high-dose tolerance. 2-5A pentasodium solution 100 mM is an important tool molecule for investigating the pathological mechanisms of viral infection; hereditary prostate cancer and leukemia[1][2].
- Molecular Weight:
- 1275.50
- Purity:
- 90
- Research Area:
- Cancer;Infection
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Solution; -20[o]C; 2 years
- Type:
- Molecular Biology Reagents: Nucleic Acids
