CDD-2789
Product Sizes
5 mg
£ POA
HY-173149-5MG
100 mg
£ POA
HY-173149-100MG
10 mg
£ POA
HY-173149-10MG
50 mg
£ POA
HY-173149-50MG
25 mg
£ POA
HY-173149-25MG
10mM/1mL
£ POA
HY-173149-10MM
About this Product
- SKU:
- HY-173149
- CAS Number:
- 3052084-77-9
- Extra Details:
- CDD-2789 is a highly selective small-molecule inhibitor targeting Activin receptor type 1 (ALK2; also known as ACVR1). It blocks the SMAD1/5 signaling pathway mediated by ALK2/ALK1; thereby effectively suppressing downstream phosphorylation events induced by BMP and activin A. In the NanoBRET cellular model; CDD-2789 exhibits an inhibitory IC50 of 0.54 µM against ALK2. CDD-2789 holds promise for research on ALK2-related diseases; including diffuse intrinsic pontine glioma (DIPG); ependymoma; endometrial cancer; melanoma; non–small cell lung cancer; colorectal cancer; and pancreatic cancer[1].
- Molecular Weight:
- 466.57
- Purity:
- 99.38
- Research Area:
- Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C; 3 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
