PD-L1/VISTA-IN-2
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HY-172396-1EACH
About this Product
- SKU:
- HY-172396
- Application:
- Antibody Microarray
- Extra Details:
- PD-L1/VISTA-IN-2 (Compound S8) is an orally active bifunctional PD-L1/VISTA inhibitor with an IC50 of 1.4 μM for PD-L1 and a KD of 2.1 μM for VISTA. PD-L1/VISTA-IN-2 can activate the tumor immune microenvironment and exert anti-cancer effects[1].
- Molecular Weight:
- 362.42
- References:
- [1]Xiao Y, et al. Discovery of bifunctional small molecules targeting PD-L1/VISTA with favorable pharmacokinetics for cancer immunotherapy. Bioorg Chem. 2025 Mar 1;157:108323.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
