OPB-3206
Product Sizes
Get quote
£ POA
HY-171776-1EACH
About this Product
- SKU:
- HY-171776
- CAS Number:
- 166245-54-1
- Extra Details:
- OPB-3206 is a selective matrix metalloproteinase (MMP) inhibitor. OPB-3206 inhibits interstitial collagenase; gelatinase A (MMP-2); gelatinase B (MMP-9) and stromelysin with IC50 values of 7×10-7 M; 5×10-6 M; 5×10-7 M and 2×10-6 M; respectively. OPB-3206 reversibly binds to the zinc-binding region of MMPs; preventing the activation of MMP-9 and reducing extracellular matrix degradation to inhibit tumor lung metastasis. OPB-3206 is promising for research of lung metastasis of osteosarcoma[1].
- Molecular Weight:
- 363.41
- References:
- [1]Kido A, et al. Inhibition of Spontaneous Rat Osteosarcoma Lung Metastasis by 3S‐[4‐(Nhydroxyamino)‐2R‐isobutylsuccinyl] amino‐1‐methoxy‐3, 4‐dihydrocarbostyril, a Novel Matrix Metalloproteinase Inhibitor[J]. Japanese journal of cancer research, 1999, 90(3): 333-341.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
