AGS-16C3F
Product Sizes
10 mg
£ POA
HY-171544-10MG
5 mg
£ POA
HY-171544-5MG
25 mg
£ POA
HY-171544-25MG
1 mg
£ POA
HY-171544-1MG
About this Product
- SKU:
- HY-171544
- Additional Names:
- AGS-16M8F
- Application:
- Antibody Microarray
- Extra Details:
- AGS-16C3F is an antibody-drug conjugate (ADC) targeting ENPP3. AGS-16C3F is composed of ENPP3-targeting Anti-ENPP3/CD203c Antibody (HY-P990315) linked to Monomethyl auristatin F (HY-15579) via a linker. AGS-16C3F has anti-tumor activity and can be used in the study of metastatic renal cell carcinoma (mRCC)[1][2].
- Purity:
- 99.81
- References:
- [1]Kollmannsberger C, et al. A Randomized Phase II Study of AGS-16C3F Versus Axitinib in Previously Treated Patients with Metastatic Renal Cell Carcinoma. Oncologist. 2021 Mar;26(3):182-e361.|[2]Zhang Y, et al. In vitro and in vivo efficacy of an anti-CD203c conjugated antibody (AGS-16C3F) in mouse models of advanced systemic mastocytosis. Blood Adv. 2019 Feb 26;3(4):633-643.
- Research Area:
- Cancer
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -80[o]C; protect from light
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
