(Rac)-P1D-34
Product Sizes
1 mg
£ POA
HY-171334-1MG
5 mg
£ POA
HY-171334-5MG
10 mg
£ POA
HY-171334-10MG
25 mg
£ POA
HY-171334-25MG
10mM/1mL
£ POA
HY-171334-10MM
About this Product
- SKU:
- HY-171334
- CAS Number:
- 2957895-04-2
- Extra Details:
- PROTAC PIN1 degrader-2 (1) is a PROTAC-based PIN1 degrader (Pink: PIN1 ligand HY-171442; Blue: cereblon ligand Thalidomide (HY-14658); Black: linker HY-W014883). PROTAC PIN1 degrader-2 (1) possesses anti-cancer activity; with IC50 values of 2248 nM (MV-4-11 cells); 3984 nM (MOLM-13); 3925 nM (HL-60); 3925 nM (HL-60); 3925 nM (HL-60); 3925 nM (HL-60) and 3925 nM (HL-60) respectively[1].
- Molecular Weight:
- 835.45
- Purity:
- 99.45
- References:
- [1]Zhoubing, et al. Compound for degrading Pin1 protein in targeted ubiquitination, and pharmaceutical composition and application thereof. Patent CN116425733A.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- PI3K/Akt/mTOR;PROTAC
