Becotatug vedotin
Product Sizes
10 mg
£ POA
HY-171265-10MG
1 mg
£ POA
HY-171265-1MG
5 mg
£ POA
HY-171265-5MG
About this Product
- SKU:
- HY-171265
- Additional Names:
- MRG003
- Extra Details:
- Becotatug vedotin (MRG003) is an Antibody-Drug Conjugate (ADC) that consists of an anti-EGFR humanized IgG1 monoclonal antibody Becotatug (HY-P990049) and MMAE (HY-15162). These two parts are connected through a valine-citrulline (valine-citrulline) linker; where the linker and MMAE constitute the ADC's Drug-Linker conjugate VcMMAE (HY-15575). Becotatug vedotin can be used for the research of cancer; such as squamous cell carcinomas of the head and neck; nasopharyngeal carcinoma[1].
- Molecular Weight:
- 149470 (average)
- Purity:
- 96.99
- References:
- [1]Qiu MZ, et al. Evaluation of Safety of Treatment With Anti-Epidermal Growth Factor Receptor Antibody Drug Conjugate MRG003 in Patients With Advanced Solid Tumors: A Phase 1 Nonrandomized Clinical Trial. JAMA Oncol. 2022 Jul 1;8(7):1042-1046.
- Research Area:
- Cancer
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -80[o]C; protect from light
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
