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Proteins and Peptides

CDD-1115

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HY-171248-1EACH
About this Product
SKU:
HY-171248
CAS Number:
3034215-86-3
Extra Details:
CDD-1115 is a potent; selective inhibitor of BMPR2 with IC50 of 1.8 nM; Kiapp of 6.2 nM. CDD-1115 inhibits bone morphogenetic protein (BMP)-mediated gene expression. BMP controls cellular processes across many tissue types; including the kidney; skeletal muscle; heart; and reproductive organs. BMP induces ectopic bone formation[1].
Molecular Weight:
546.62
References:
[1]Modukuri RK, et al. Discovery of Highly Potent and BMPR2-Selective Kinase Inhibitors Using DNA-Encoded Chemical Library Screening. J Med Chem. 2023 Feb 9;66(3):2143-2160.
Research Area:
Endocrinology; Cardiovascular Disease
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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