1-Acetyl-DHAP
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HY-171229-1EACH
About this Product
- SKU:
- HY-171229
- CAS Number:
- 2267338-53-2
- Extra Details:
- 1-Acetyl-DHA (Compound 7) is a substrate of the phosphotriesterase homology protein (PHP) and can be hydrolyzed by PHP with a kcat/km value of 100 M-1s-1. The level of 1-Acetyl-DHA is regulated by mTORC1 and is negatively correlated with the nuclear acetate level. 1-Acetyl-DHA plays an important role in cellular metabolism and the regulation of histone acetylation[1][2].
- Molecular Weight:
- 212.09
- References:
- [1]Nemmara VV, et al. Substrate Profile of the Phosphotriesterase Homology Protein from Escherichia coli. Biochemistry. 2018 Oct 30;57(43):6219-6227.|[2]Zhang JJ, et al. Nuclear dihydroxyacetone phosphate signals nutrient sufficiency and cell cycle phase to global histone acetylation. Nat Metab. 2021 Jun;3(6):859-875.
- Research Area:
- Others
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
