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Proteins and Peptides

PD-L1/VISTA-IN-1

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HY-170793-1EACH
About this Product
SKU:
HY-170793
Application:
Antibody Microarray
CAS Number:
2978623-09-3
Extra Details:
PD-L1/VISTA-IN-1 (Compound P17) is an orally active dual-target inhibitor of PD-L1 and VISTA. PD-L1/VISTA-IN-1 can block the PD-1/PD-L1 interaction (IC50: 0.1492 μM) and the VISTA pathway (KD: 0.2723 μM); thereby reactivating T cells. PD-L1/VISTA-IN-1 has anti-tumor activity[1].
Molecular Weight:
408.45
References:
[1]Sun C, et al. Novel PD-L1/VISTA Dual Inhibitor as Potential Immunotherapy Agents. J Med Chem. 2025 Jan 9;68(1):156-173.
Research Area:
Cancer
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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