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APL-1081

Product Sizes
5 mg
£ POA
HY-169322-5MG
10 mg
£ POA
HY-169322-10MG
1 mg
£ POA
HY-169322-1MG
About this Product
SKU:
HY-169322
Additional Names:
Mal-Exo-EVC-MMAE
Application:
Antibody Microarray
CAS Number:
2921735-80-8
Extra Details:
APL-1081 (Mal-Exo-EVC-MMAE) is part of an antibody-conjugated active molecule (ADC). APL-1081 is conjugated with an ADC linker (peptide Mal-Exo-EEVC) and a potent tubulin polymerization inhibitor; MMAE (HY-15162)[1].
Molecular Weight:
1502.79
Purity:
99.79
References:
[1]Watanabe T, et al. Exo-Cleavable Linkers: Enhanced Stability and Therapeutic Efficacy in Antibody–Drug Conjugates[J]. Journal of Medicinal Chemistry, 2024.
Research Area:
Cancer
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C (Powder; sealed storage; away from moisture and light)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Pathway:
Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton
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