PD-1/PD-L1-IN-52
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HY-168081-1EACH
About this Product
- SKU:
- HY-168081
- Application:
- Antibody Microarray
- CAS Number:
- 2856391-46-1
- Extra Details:
- PD-1/PD-L1-IN-52 (Compound III-5) is an orally active PD-1/PD-L1 inhibitor that blocks the interaction between PD-1 and PD-L1; with an IC50 of 109.9 nM. PD-1/PD-L1-IN-52 exhibits antitumor activity in a C57BL/6 mouse xenograft model implanted with human PD-1-expressing MC38 colon cancer cells; with a TGI of 49.6%[1].
- Molecular Weight:
- 870.39
- References:
- [1]Xia Y, et al. Design, synthesis, and antitumor activity evaluation of 1,2,3-triazole derivatives as potent PD-1/PD-L1 inhibitors. Bioorg Chem. 2024 Sep 7;153:107813.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
