(E/Z)-Elafibranor
Product Sizes
10 mg
£ POA
HY-16737A-10MG
50 mg
£ POA
HY-16737A-50MG
1 mg
£ POA
HY-16737A-1MG
25 mg
£ POA
HY-16737A-25MG
5 mg
£ POA
HY-16737A-5MG
About this Product
- SKU:
- HY-16737A
- Additional Names:
- (E/Z)-GFT505
- Application:
- Electron Microscopy
- CAS Number:
- 824932-88-9
- Extra Details:
- (E/Z)-Elafibranor ((E/Z)-GFT505) is a PPARα/δ agonist with EC50s of 45 and 175 nM; respectively[1][2][3].
- Molecular Weight:
- 384.49
- Purity:
- 98.36
- References:
- [1]Liu ZM, et al. Early investigational drugs targeting PPAR-α for the treatment of metabolic disease.Expert Opin Investig Drugs. 2015 May;24(5):611-21.|[2]Ratziu V, et al. Elafibranor, an Agonist of the Peroxisome Proliferator-Activated Receptor-α and -δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening. Gastroenterology. 2016 May;150(5):1147-1159.|[3]Hanf R, et al. The dual peroxisome proliferator-activated receptor alpha/delta agonist GFT505 exerts anti-diabetic effects in db/db mice without peroxisome proliferator-activated receptor gamma-associated adverse cardiac effects.Diab Vasc Dis Res. 2014 No
- Research Area:
- Metabolic Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
