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BCN-DOTA-GA

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HY-164577-1EACH
About this Product
SKU:
HY-164577
Application:
Antibody Microarray
CAS Number:
2416980-98-6
Extra Details:
BCN-DOTA-GA is a cyclooctyne-linked DOTA chelator and prosthetic group. BCN-DOTA-GA forms a stable complex with 89zirconium when radiolabeled via a two-step basic pH adjustment method at 90°C. BCN-DOTA-GA conjugates with PAN-tetrazene via click chemistry at 37°C to form a radiolabeled antibody conjugate. BCN-DOTA-GA; when conjugated to panitumumab as BCN-Zr-DOTA-GA-PAN; shows stability in whole human serum for up to 7 days at 37°C. BCN-DOTA-GA; when conjugated to panitumumab as BCN-Zr-DOTA-GA-PAN; exhibits kinetic inertness against EDTA challenge.BCN-DOTA-GA can be used for the research of her1-expressing colorectal cancers[1].
Molecular Weight:
694.77
Research Area:
Cancer
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
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