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Proteins and Peptides

HS-345

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HY-164483-1EACH
About this Product
SKU:
HY-164483
CAS Number:
1462329-41-4
Extra Details:
HS-345 is a TrkA/Ak inhibitor with significant anti-pancreatic cancer effects. HS-345 inhibits the growth and proliferation of pancreatic cancer cells by targeting the TrkA/Akt signaling pathway; while also inducing apoptosis. Additionally; HS-345 suppresses blood vessel formation by decreasing the expression of HIF-1α and VEGF. HS-345 holds promise for research in pancreatic cancer[1].
Molecular Weight:
394.45
References:
[1]Seo JH, et al. Anti-cancer effect of HS-345, a new tropomyosin-related kinase A inhibitor, on human pancreatic cancer. Cancer Lett. 2013 Sep 28;338(2):271-81.
Research Area:
Cancer
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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