ADC Control Human IgG1-vcMMAE (solution)
Product Sizes
5 mg
£ POA
HY-164153-5MG
1 mg
£ POA
HY-164153-1MG
About this Product
- SKU:
- HY-164153
- Application:
- Antibody Microarray
- Extra Details:
- ADC Control Human IgG1-vcMMAE (solution) is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-vcMMAE and can inhibit tubulin polymerization. The antibody portion is Human IgG1 kappa; Isotype Control (HY-P99001); and the drug-linker conjugate for ADC is vcMMAE (HY-15575)[1].
- Molecular Weight:
- 147946 (average)
- Purity:
- 98.08
- References:
- [1]Tushar D Nichakawade, et al. TRBC1-targeting antibody-drug conjugates for the treatment of T cell cancers. Nature. 2024 Apr;628(8007):416-423. |[2]Okeley, et al. Intracellular Activation of SGN-35, a Potent Anti-CD30 Antibody-Drug Conjugate. Clinical Cancer Research (2010), 16(3), 888-897.|[3]Lisa Buckel, et al. Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery. Cancer Res. 2015 Apr 1;75(7):1376-87.
- Research Area:
- Cancer
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -80[o]C; protect from light
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Pathway:
- Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton
