PD-1/PD-L1-IN-49
Product Sizes
Get quote
£ POA
HY-163844-1EACH
About this Product
- SKU:
- HY-163844
- Extra Details:
- PD-1/PD-L1-IN-49 (compound 1c) is a potent inhibitor of PD-1/PD-L1; with the IC50 of 77 nM. PD-1/PD-L1-IN-49 activates Jurkat T cells; reflecting successful blockade of the PD-1/PD-L1 immune checkpoint[1].
- Molecular Weight:
- 492.57
- References:
- [1]Julia Zaber, et al. N-methylmorpholine incorporation into the structure of biphenyl leads to the bioactive inhibitor of PD-1/PD-L1 interaction. Bioorg Med Chem Lett. 2024 Jul 10:110:129882.
- Research Area:
- Cancer; Inflammation/Immunology
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
