(S)-CE-123
Product Sizes
5 mg
£ POA
HY-163384-5MG
25 mg
£ POA
HY-163384-25MG
100 mg
£ POA
HY-163384-100MG
50 mg
£ POA
HY-163384-50MG
10 mg
£ POA
HY-163384-10MG
About this Product
- SKU:
- HY-163384
- CAS Number:
- 2378384-49-5
- Extra Details:
- (S)-CE-123 is a potent; selective; and novel atypical dopamine transporter (DAT) inhibitor with an EC50 of 2.76 μM in uptake inhibition assays conducted in HEK293 cells stably expressing human isoforms of DAT. (S)-CE-123; a Modafinil analogue; is able to penetrate the blood–brain barrier. (S)-CE-123 improves cognitive and motivational processes in experimental animals[1][2].
- Molecular Weight:
- 313.44
- References:
- [1]Renee A Rotolo, et al. The Novel Atypical Dopamine Uptake Inhibitor (S)-CE-123 Partially Reverses the Effort-Related Effects of the Dopamine Depleting Agent Tetrabenazine and Increases Progressive Ratio Responding. Front Pharmacol. 2019 Jun 28:10:682. |[2]Eduardo R. Perez Gonzalez, et al. Process Development and Scale-Up of a Novel Atypical DAT Inhibitor (S)-CE-123. ACS Omega 2024, March 4.
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Neuronal Signaling
