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Proteins and Peptides

PD-1/PD-L1-IN-39

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HY-163307-1EACH
About this Product
SKU:
HY-163307
Application:
Antibody Microarray
Extra Details:
PD-1/PD-L1-IN-39 (X 14) is an orally active PD-1/PD-L1 inhibitor with a IC50 value of 15.73 nM. PD-1/ PD-L1-in-39 has a good binding affinity for human and mouse PD-L1; with KD values of 14.62 nM and 392 nM; respectively. PD-1/PD-L1-IN-39 has antitumor activity[1].
Molecular Weight:
426.87
References:
[1]Xu Y, et al. Discovery of Highly Potent Small-Molecule PD-1/PD-L1 Inhibitors with a Novel Scaffold for Cancer Immunotherapy. J Med Chem. 2024 Feb 13.
Research Area:
Cancer
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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