Lonaprisan
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HY-16290-1EACH
About this Product
- SKU:
- HY-16290
- Additional Names:
- ZK 230211; BAY86 5044
- Application:
- Electron Microscopy
- CAS Number:
- 211254-73-8
- Extra Details:
- Lonaprisan (ZK 230211; BAY86 5044) is an antagonist for progesterone receptor; with IC50 of 3.6 pM and 2.5 pM for PR-A and PR-B; respectively. Lonaprisan exhibits antiprogestagenic activity in rabbits; interrupts early pregnancy in rats; and exhibits antitumor efficacy against DMBA (HY-W011845)-induced mammary tumor. Lonaprisan reveals antiglucocorticoid and antiandrogenic effect[1].
- Molecular Weight:
- 508.52
- References:
- [1]Fuhrmann U, et al., Synthesis and biological activity of a novel, highly potent progesterone receptor antagonist. J Med Chem. 2000 Dec 28;43(26):5010-6.
- Research Area:
- Endocrinology
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
