BSO-07
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HY-162886-1EACH
About this Product
- SKU:
- HY-162886
- Extra Details:
- BSO-07 is a ROS/JNK activator with significant anticancer effects; having an IC50 value of 24.81 μM against human breast cancer (BC) cells. BSO-07 induces apoptosis (Apoptosis) and paraptosis by activating JNK and increasing ROS levels; including enhancing the expression of apoptosis-associated proteins such as PARP; Bax; phosphorylated p53; ATF4; and CHOP; while decreasing the levels of anti-apoptotic proteins like Bcl-2; Bcl-xL; and Survivin. BSO-07 holds promise for research in the field of breast cancer[1].
- Molecular Weight:
- 427.94
- References:
- [1]Kim NY, et al. Oxazine drug-seed induces paraptosis and apoptosis through reactive oxygen species/JNK pathway in human breast cancer cells. Transl Oncol. 2024 Nov;49:102101.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
