BAL-0028
Product Sizes
100 mg
£ POA
HY-162333-100MG
50 mg
£ POA
HY-162333-50MG
25 mg
£ POA
HY-162333-25MG
10 mg
£ POA
HY-162333-10MG
5 mg
£ POA
HY-162333-5MG
10mM/1mL
£ POA
HY-162333-10MM
About this Product
- SKU:
- HY-162333
- CAS Number:
- 2842012-69-3
- Extra Details:
- BAL-0028 is a reversible inhibitor of NLRP3 activation with an IC50 value of 25 nM. BAL-0028 binds closely to the NACHT domain of the NLRP3 with KD values of 104-123 nM. BAL-0028 can inhibit the secretion of IL-1β and has anti-inflammatory activity[1].
- Molecular Weight:
- 403.45
- Purity:
- 99.86
- References:
- [1]Hartman G, et al. The discovery of novel and potent indazole NLRP3 inhibitors enabled by DNA-encoded library screening. Bioorg Med Chem Lett. 2024 Feb 28;102:129675.
- Research Area:
- Inflammation/Immunology
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Immunology/Inflammation
