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Proteins and Peptides

PD-1/PD-L1-IN-44

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HY-161518-1EACH
About this Product
SKU:
HY-161518
Application:
Antibody Microarray
CAS Number:
3043669-06-0
Extra Details:
PD-1/PD-L1-IN-44 (Compound 22) selectively inhibits PD-1/PD-L1 proteins (IC50=1.21 nM). PD-1/PD-L1-IN-44 inhibits tumor growth without toxicity in animal models and increases CD8+ cell infiltration[1].
Molecular Weight:
562.61
References:
[1]Zhang Y, et al. Improving tumor sensitivity by the introduction of an ester chain to triaryl derivatives targeting PD-1/PD-L1. Eur J Med Chem. 2024 May 5;271:116433.
Research Area:
Cancer
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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