(rac)-Lomedeucitinib
Product Sizes
5 mg
£ POA
HY-160144S2-5MG
1 mg
£ POA
HY-160144S2-1MG
10 mg
£ POA
HY-160144S2-10MG
About this Product
- SKU:
- HY-160144S2
- Additional Names:
- (rac)-BMS-986322
- CAS Number:
- 2328064-33-9
- Extra Details:
- (rac)-Lomedeucitinib ((rac)-BMS-986322) is the racemate of Lomedeucitinib. Lomedeucitinib (BMS-986322) is a tyrosine protein kinase (TYK2) inhibitor. Lomedeucitinib has anti-inflammatory activity and significant inhibitory effect on IFNα (IC50=0.047 μM) production downstream of IL-12/TYK2. Lomedeucitinib is indicated for the study of plaque psoriasis and pruritus[1][2][3].
- Molecular Weight:
- 419.47
- Purity:
- 98.11
- References:
- [1]Drakos A, et al. Emerging Oral Therapies for the Treatment of Psoriasis: A Review of Pipeline Agents[J]. Pharmaceutics, 2024, 16(1): 111.|[2]Zhang K, et al. Development and therapeutic implications of tyrosine kinase 2 inhibitors[J]. Journal of Medicinal Chemistry, 2023, 66(7): 4378-4416.|[3]Andrew Nicholas Billin, et al. Il-31 modulators for treating fxr-induced pruritis. WO2022266444A1. 2022-06-17
- Research Area:
- Others
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Others
