TDP-43 degrader-1
Product Sizes
1 mg
£ POA
HY-160115-1MG
About this Product
- SKU:
- HY-160115
- CAS Number:
- 2902692-25-3
- Extra Details:
- TDP-43 degrader-1 (Compound example 7) is a TDP-43 degrader. TDP-43 degrader-1 reduces the aggregation of TDP-43-positive HuR stress granules in cells and promotes the relocalization of abnormally distributed TDP-43 in the cytoplasm to the nucleus. TDP-43 degrader-1 can be used in the study of amyotrophic lateral sclerosis and Alzheimer's disease[1].
- Molecular Weight:
- 455.55
- Purity:
- 98.92
- References:
- [1]Solas Dennis, et al. Preparation of substituted isoquinolines for the treatment of ALS. United States, US20230037538 A1 2023-02-09
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C; 3 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage
