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Molecular Biology

AA3-DLin

Product Sizes
5 mg (35.76 mM * 200 μL in Ethanol)
£ POA
HY-159700-5MG
10 mg (35.76 mM * 400 μL in Ethanol)
£ POA
HY-159700-10MG
50 mg (35.76 mM * 2 mL in Ethanol)
£ POA
HY-159700-50MG
100 mg (35.76 mM * 4 mL in Ethanol)
£ POA
HY-159700-100MG
25 mg (35.76 mM * 1 mL in Ethanol)
£ POA
HY-159700-25MG
About this Product
SKU:
HY-159700
CAS Number:
3027565-91-6
Extra Details:
AA3-DLin is an ionizable cationic lipid with a pKa value of 5.8. AA3-DLin is used to delivery mRNA combined with lipid nanoparticles (LNPs). AA3-DLin LNP COVID-19 vaccines encapsulating SARS CoV-2 spike mRNAs successfully induces strong immunogenicity in a BALB/c mouse model[1].
Molecular Weight:
699.10
Purity:
99.0
References:
[1]Li Z, et al. Enzyme-Catalyzed One-Step Synthesis of Ionizable Cationic Lipids for Lipid Nanoparticle-Based mRNA COVID-19 Vaccines. ACS Nano. 2022 Nov 22;16(11):18936-18950.
Research Area:
Infection
Shipping Conditions:
Blue Ice
Storage Conditions:
Solution; -20[o]C; 2 years
Type:
Molecular Biology Reagents: Nucleic Acids
Pathway:
Metabolic Enzyme/Protease
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