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Proteins and Peptides

(1S;2S;3R)-PLX-4545

Product Sizes
5 mg
£ POA
HY-159647B-5MG
10 mg
£ POA
HY-159647B-10MG
25 mg
£ POA
HY-159647B-25MG
50 mg
£ POA
HY-159647B-50MG
About this Product
SKU:
HY-159647B
CAS Number:
2892066-42-9
Extra Details:
(1S;2S;3R)-PLX-4545 is the (1S;2S;3R) enantiomer of PLX-4545 (HY-159647). PLX-4545 is an orally active and selective cereblon-based molecular glue degrader of IKZF2 (zinc finger transcription factor Helios). PLX-4545 can reprogram immunosuppressive regulatory T cells into pro-inflammatory effector T cells; thereby enhancing anti-tumor immune responses[1].
Molecular Weight:
473.56
Purity:
91.78
Research Area:
Cancer
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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