ISTH0036 (sodium) scrambled negative control
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HY-158821B-1EACH
About this Product
- SKU:
- HY-158821B
- Extra Details:
- ISTH0036 sodium scrambled negative control is the sequence scrambled negative control of ISTH0036 sodium (HY-158821A). ISTH0036 sodium is a phosphorothioate LNA-modified antisense oligonucleotide gapmer that selectively targets and downregulates TGF-β2 mRNA. ISTH0036 sodium suppresses TGF-β2 expression; reduces choroidal neovascularization and vascular leakage; inhibits fibrosis; blocks epithelial-to-mesenchymal transition; and inhibits angiogenesis while promoting bleb survival. ISTH0036 sodium exhibits long-lasting; dose-dependent ocular tissue distribution and target engagement in rabbit and non-human primate eyes. ISTH0036 sodium can be used for the study of various ocular disorders; such as glaucoma and neovascular retinal diseases.
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Ambient
- Type:
- Molecular Biology Reagents: Nucleic Acids
