ISTH0036 (sodium)
Product Sizes
10 mg
£ POA
HY-158821A-10MG
1 mg
£ POA
HY-158821A-1MG
5 mg
£ POA
HY-158821A-5MG
About this Product
- SKU:
- HY-158821A
- Extra Details:
- ISTH0036 sodium is a phosphorothioate LNA-modified antisense oligonucleotide gapmer that selectively targets and downregulates TGF-β2 mRNA. ISTH0036 sodium suppresses TGF-β2 expression; reduces choroidal neovascularization and vascular leakage; inhibits fibrosis; blocks epithelial-to-mesenchymal transition; and inhibits angiogenesis while promoting bleb survival. ISTH0036 sodium exhibits long-lasting; dose-dependent ocular tissue distribution and target engagement in rabbit and non-human primate eyes. ISTH0036 sodium can be used for the study of various ocular disorders; such as glaucoma and neovascular retinal diseases[1][2][3].
- Purity:
- 96.85
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; sealed storage; away from moisture)
- Type:
- Molecular Biology Reagents: Nucleic Acids
