HG-14-10-04
Product Sizes
25 mg
£ POA
HY-15801-25MG
5 mg
£ POA
HY-15801-5MG
100 mg
£ POA
HY-15801-100MG
50 mg
£ POA
HY-15801-50MG
10 mg
£ POA
HY-15801-10MG
10mM/1mL
£ POA
HY-15801-10MM
About this Product
- SKU:
- HY-15801
- CAS Number:
- 1356962-34-9
- Extra Details:
- HG-14-10-04 is a potent ALK and mutant EGFR inhibitor with IC50s of 20 nM; 15.6 nM; 22.6 nM and 124.5 nM for ALK; EGFRLR/TM; EGFR19del/TM/CS and EGFRLR/TM/CS; respectively. HG-14-10-04 can be used to research anticancer[1][2].
- Molecular Weight:
- 532.08
- Purity:
- 99.09
- References:
- [1]U.S. Pat. Appl. Publ. (2012), US 20120028924 A1|[2]Chen H, et al. Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-Generation Epidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations. J Med Chem. 2022 May 12;65(9):6840-6858.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
