PD-1-IN-25
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HY-157055-1EACH
About this Product
- SKU:
- HY-157055
- Application:
- Antibody Microarray
- CAS Number:
- 2413100-40-8
- Extra Details:
- PD-1-IN-25 (compound 43) is a potent PD-1/PD-L1 interaction inhibitor with an IC50 value of 10.2 nM in the HTRF assay. PD-1-IN-25 can promote CD8+ T cell activation through inhibiting PD-1/PD-L1 cellular signaling. PD-1-IN-25 delays the tumor growth[1].
- Molecular Weight:
- 725.13
- References:
- [1]Zilan Song, et al. Design, Synthesis, and Pharmacological Evaluation of Biaryl-Containing PD-1/PD-L1 Interaction Inhibitors Bearing a Unique Difluoromethyleneoxy Linkage. J Med Chem. 2021 Nov 25;64(22):16687-16702.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
