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Proteins and Peptides

(4′R)-TGR5 Receptor Agonist 4

Product Sizes
1 mg
£ POA
HY-156830A-1MG
25 mg
£ POA
HY-156830A-25MG
50 mg
£ POA
HY-156830A-50MG
5 mg
£ POA
HY-156830A-5MG
10 mg
£ POA
HY-156830A-10MG
10mM/1mL
£ POA
HY-156830A-10MM
About this Product
SKU:
HY-156830A
Application:
Electron Microscopy
CAS Number:
1872436-55-9
Extra Details:
(4′R)-TGR5 Receptor Agonist 4 is the R enantiomer of TGR5 Receptor Agonist 4 (HY-156830). TGR5 Receptor Agonist 4 is an agonist of Bile Acid Receptor (TGR5); with EC50 for hTGR5 and mTGR5 of 2 nM and 3 nM; respectively. TGR5 Receptor Agonist 4 plays important roles in hypoglycemic and weight loss[1].
Molecular Weight:
470.95
Purity:
99.90
References:
[1]Sylvain Picon, et al. Discovery, Structure-Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5. J Med Chem. 2023 Sep 14;66(17):11732-11760.
Research Area:
Metabolic Disease
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
GPCR/G Protein
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