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Proteins and Peptides

(Rac)-GDC-2992

Product Sizes
1 mg
£ POA
HY-156751-1MG
5 mg
£ POA
HY-156751-5MG
About this Product
SKU:
HY-156751
Additional Names:
(Rac)-RO7656594; PROTAC AR Degrader-6
Application:
Antibody Microarray
CAS Number:
2753650-84-7
Extra Details:
(Rac)-GDC-2992 (Compound 1) is a PROTAC androgen receptor degrader (DC50: 10 nM in VCaP cell). (Rac)-GDC-2992 blocks the process of androgen receptor transduction and also degrades the receptor itself. (Rac)-GDC-2992 can be used for prostate cancer research. Pink: AR ligand (HY-130845); Blue: E3 ligase ligand (HY-W1003189); Black: linker (HY-169975)[1].
Molecular Weight:
819.39
Purity:
95.00
References:
[1]Lu H.F, et al. 酞嗪酮类化合物及其制备方法和医药用途. China, WO2021249534 A1.2021-12-16.
Research Area:
Cancer
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C (Powder; protect from light; stored under nitrogen)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
PROTAC;Vitamin D Related/Nuclear Receptor
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