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Proteins and Peptides

(S)-Tersolisib

Product Sizes
5 mg
£ POA
HY-156681A-5MG
25 mg
£ POA
HY-156681A-25MG
50 mg
£ POA
HY-156681A-50MG
10 mg
£ POA
HY-156681A-10MG
100 mg
£ POA
HY-156681A-100MG
About this Product
SKU:
HY-156681A
Additional Names:
(S)-STX-478; (S)-STX-478-101; (S)-LY4064809
CAS Number:
2883540-91-6
Extra Details:
(S)-STX-478 is the S-enantiomer of STX-478. STX-478 is a selective inhibitor of PI3Kα mutants; preventing metabolic dysfunction and demonstrating antitumor activity in xenograft mouse models with PI3Kα mutant tumors[1].
Molecular Weight:
401.29
Purity:
99.18
References:
[1]Buckbinder L, et al. STX-478, a mutant-selective, allosteric PI3Kα inhibitor spares metabolic dysfunction and improves therapeutic response in PI3Kα-mutant xenografts[J]. Cancer Discovery, 2023, 13(11): 2432-2447.
Research Area:
Cancer
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
PI3K/Akt/mTOR
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