FTO-IN-10
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HY-156405-1EACH
About this Product
- SKU:
- HY-156405
- Application:
- Electron Microscopy
- Extra Details:
- FTO-IN-10 (compound 7) is a potent human demethylase FTO (the fat mass and obesity-associated protein) inhibitor with an IC50 of 4.5 μM. FTO-IN-10 enters the FTO’s structural domain II binding pocket through hydrophobic and hydrogen bonding interactions. FTO-IN-10 induces DNA damage and autophagic cell death in A549 cells[1].
- Molecular Weight:
- 388.42
- References:
- [1]Chao Ge, et al. Novel 1,8-Naphthalimide Derivatives As Antitumor Agents and Potent Demethylase Inhibitors. ACS Med. Chem. Lett. 2023.
- Research Area:
- Metabolic Disease
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
