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Proteins and Peptides

PD-1/PD-L1-IN-33

Product Sizes
25 mg
£ POA
HY-155959-25MG
100 mg
£ POA
HY-155959-100MG
10 mg
£ POA
HY-155959-10MG
50 mg
£ POA
HY-155959-50MG
5 mg
£ POA
HY-155959-5MG
10mM/1mL
£ POA
HY-155959-10MM
About this Product
SKU:
HY-155959
Application:
Antibody Microarray
CAS Number:
2975602-78-7
Extra Details:
PD-1/PD-L1-IN-33 (Compound N11) is a PD-1/PD-L1 inhibitor. PD-1/PD-L1-IN-33 inhibits PD-1 and PD-L1 interaction with an IC50: 6.3 nM. PD-1/PD-L1-IN-33 promotes T-cell proliferation; activation; and infiltration into tumor spheres. PD-1/PD-L1-IN-33 has immunomodulatory and anticancer activity[1].
Molecular Weight:
425.53
Purity:
99.78
References:
[1]Yangyang Meng, et al. Novel 4-Arylindolines Containing a Pyrido[3,2-d]pyrimidine Moiety as the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction Inhibitors for Tumor Immunotherapy. J. Med. Chem. 2023.
Research Area:
Cancer
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Immunology/Inflammation
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