Auristatin F
Product Sizes
25 mg
£ POA
HY-15583-25MG
10 mg
£ POA
HY-15583-10MG
5 mg
£ POA
HY-15583-5MG
100 mg
£ POA
HY-15583-100MG
50 mg
£ POA
HY-15583-50MG
About this Product
- SKU:
- HY-15583
- Application:
- Antibody Microarray
- CAS Number:
- 163768-50-1
- Extra Details:
- Auristatin F is a potent cytotoxin in antibo-conjugated agents and an analogue of MMAF. Auristatin F is a potent microtubule inhibitor and vascular damaging agent (VDA). Auristatin F inhibits cell division by preventing tubulin aggregation.Auristatin F can be used in antibody-drug conjugates (ADC) [1][2].
- Molecular Weight:
- 745.99
- Purity:
- 99.58
- References:
- [1]Roy S, et al. SMI-Ribosome inactivating protein conjugates selectively inhibit tumor cell growth. Chem Commun (Camb). 2017 Apr 11;53(30):4234-4237.|[2]Park MH, et, al. Pharmacokinetic and Metabolism Studies of Monomethyl Auristatin F via Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry. Molecules. 2019 Jul 29;24(15):2754.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Pathway:
- Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton
