Auristatin E
Product Sizes
50 mg
£ POA
HY-15582-50MG
500 mg
£ POA
HY-15582-500MG
250 mg
£ POA
HY-15582-250MG
100 mg
£ POA
HY-15582-100MG
1 g
£ POA
HY-15582-1G
About this Product
- SKU:
- HY-15582
- Application:
- Antibody Microarray
- CAS Number:
- 160800-57-7
- Extra Details:
- Auristatin E is a cytotoxic microtubule polymerization inhibitor with potent and selective antitumor activity. Auristatin E is a cytotoxin in antibody-drug conjugates (ADC). Auristatin E inhibits cell division by blocking the polymerisation of tubulin; promising for research in B-cell malignancies. Auristatin E; a synthetic analogue of the Dolastatin 10 (HY-15580); is linear peptides comprised of four amino acids[1][2][3].
- Molecular Weight:
- 732.01
- Purity:
- 99.89
- References:
- [1]MADDON Paul J, et al. PSMA ANTIBODIES AND PROTEIN MULTIMER. 2002 October 23. WO 03/034903 A2|[2]Peter D. Senter, et al. PENTAPEPTIDE COMPOUNDS AND USES RELATED THERETO. 2005 Jan. 13. US 2005/0009751 A l.|[3]LAW, Che-Leung, et al. TREATMENT OF IMMUNOLOGICAL DISORDERS 5 USING ANTI-CD30 ANTIBODIES. 2002 November 20. WO 03/043583 A2.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; protect from light; stored under nitrogen)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Pathway:
- Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton
