PD-L1-IN-3
Product Sizes
5 mg
£ POA
HY-155101-5MG
10 mg
£ POA
HY-155101-10MG
100 mg
£ POA
HY-155101-100MG
50 mg
£ POA
HY-155101-50MG
25 mg
£ POA
HY-155101-25MG
10mM/1mL
£ POA
HY-155101-10MM
About this Product
- SKU:
- HY-155101
- Application:
- Antibody Microarray
- CAS Number:
- 2953044-29-4
- Extra Details:
- PD-L1-IN-3 (Compound 4a) is a compound that targets PD-1/PD-L1; the IC50 value and EC50 value is 4.97nM and 2.70 μM for inhibit PD-L1 and Jurkat T cells; respectively. PD-L1-IN-3 can bind PD-L1 dimer to prevent PD-1 binding to PD-L1; therefore blocking PD-1 signaling. PD-L1-IN-3 can be used for lung cancer and melanoma diseases research[1].
- Molecular Weight:
- 374.86
- Purity:
- 99.69
- References:
- [1]Ważyńska MA, et al. Design, Synthesis, and Biological Evaluation of 2-Hydroxy-4-phenylthiophene-3-carbonitrile as PD-L1 Antagonist and Its Comparison to Available Small Molecular PD-L1 Inhibitors. J Med Chem. 2023 Jul 27;66(14):9577-9591.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Immunology/Inflammation
