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Proteins and Peptides

(3S)-Tanzisertib (hydrochloride)

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HY-15495B-1EACH
About this Product
SKU:
HY-15495B
Additional Names:
(3S)-CC-930 (hydrochloride)
CAS Number:
2517855-91-1
Extra Details:
(3S)-Tanzisertib (hydrochloride) ((3S)-CC-930 (hydrochloride)) is an orally active JNK inhibitor (IC50 values for JNK1; JNK2; and JNK3 are 61; 7; and 6 nM; respectively). (3S)-Tanzisertib (hydrochloride) selectively inhibits ERK1; p38α; and EGFR (IC50 = 0.48; 3.4; and 0.38 μM; respectively). (3S)-Tanzisertib (hydrochloride) inhibits LPS-induced TNFα production in an acute rat PK-PD model. (3S)-Tanzisertib (hydrochloride) can be used in idiopathic pulmonary fibrosis (IPF) research[1].
Molecular Weight:
484.90
References:
[1]Plantevin Krenitsky V, et al. Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1433-8.
Research Area:
Inflammation/Immunology
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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