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Proteins and Peptides

PD-1/PD-L1-IN-34

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HY-154869-1EACH
About this Product
SKU:
HY-154869
CAS Number:
2924403-17-6
Extra Details:
PD-1/PD-L1-IN-34 (Compound (1S;2S)-A25) inhibits PD-1/PD-L1 interaction (IC50=0.029 μM); with a selected binding affinity with PD-L1 (KD=0.1554 μM). PD-1/PD-L1-IN-34 inhibits tumor growth by activating the immune microenvironment[1].
Molecular Weight:
565.10
References:
[1]Jing T, et al. Discovery and Optimization of Novel Biphenyl Derivatives Bearing Cyclopropyl Linkage as Potent Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Inhibitors. J Med Chem. 2023 May 25;66(10):6811-6835.
Research Area:
Cancer; Inflammation/Immunology
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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