Gintemetostat
Product Sizes
5 mg
£ POA
HY-154812-5MG
100 mg
£ POA
HY-154812-100MG
10 mg
£ POA
HY-154812-10MG
50 mg
£ POA
HY-154812-50MG
25 mg
£ POA
HY-154812-25MG
10mM/1mL
£ POA
HY-154812-10MM
About this Product
- SKU:
- HY-154812
- Additional Names:
- KTX-1001
- Application:
- Antibody Microarray
- CAS Number:
- 2604513-16-6
- Extra Details:
- Gintemetostat is an orally available; highly specific NSD2/MMSET histone methyltransferase inhibitor with human NSD2 IC50 values ranging 0.460-2.17 nM and NSD2 SET domain IC50 of 2.32 nM and Kd values ranging 6.3-70.4 nM[1][4].Gintemetostat reduces H3K36me2 levels; impairs multiple myeloma cell adhesion and colony formation; enhances cytotoxicity; boosts T-cell activation; and sensitizes resistant multiple myeloma cells to other agents[1][2][6].Gintemetostat can be used for the research of multiple myeloma and relapsed and refractory multiple myeloma[1][2][3][4][5][6].
- Molecular Weight:
- 546.52
- Purity:
- 99.81
- References:
- [1]Roberts M F, et al. 6-Methoxyflavonols from Brickellia veronicaefolia (compositae)[J]. Phytochemistry, 1980, 19(1): 127-129.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Epigenetics
