5′-Azido-5′-deoxyadenosine
Product Sizes
5 mg
£ POA
HY-154054-5MG
10 mg
£ POA
HY-154054-10MG
25 mg
£ POA
HY-154054-25MG
About this Product
- SKU:
- HY-154054
- Application:
- Antibody Microarray
- CAS Number:
- 737-76-8
- Extra Details:
- 5′-Azido-5′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis; induction of apoptosis; etc[1]. 5′-Azido-5′-deoxyadenosine is a click chemistry reagent; it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Molecular Weight:
- 292.25
- References:
- [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Molecular Biology Reagents: Nucleic Acids
- Pathway:
- Cell Cycle/DNA Damage
