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Molecular Biology

Inactive ASO (in vivo) sodium

Product Sizes
10 mg
£ POA
HY-153734-10MG
5 mg
£ POA
HY-153734-5MG
1 mg
£ POA
HY-153734-1MG
25 mg
£ POA
HY-153734-25MG
50 mg
£ POA
HY-153734-50MG
100 mg
£ POA
HY-153734-100MG
About this Product
SKU:
HY-153734
Extra Details:
Inactive ASO (in vivo) sodium is an inactive Antisense Oligonucleotide. ASO is a class of oligonucleotide molecules; usually composed of 20-30 bases; used to interfere with or regulate gene expression. Inactive ASO (in vivo) sodium is not targeted in the rodent genome and can be used as a negative control for Tofersen. Inactive ASO (in vivo) sodium contains thiophosphate skeleton modification and MOE modification. Cytosine in Inactive ASO (in vivo) is 5' methylcytosine. See References for the location of chemical modifications
Molecular Weight:
N/A
Purity:
92.18
References:
[1]McCampbell A, Cole T, Wegener AJ, et al. Antisense oligonucleotides extend survival and reverse decrement in muscle response in ALS models. J Clin Invest. 2018;128(8):3558-3567.
Research Area:
Others
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C (Powder; sealed storage; away from moisture)
Type:
Molecular Biology Reagents: Nucleic Acids
Pathway:
Others
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