AS-Patisiran (sodium)
Product Sizes
10 mg
HY-153609-10MG
5 mg
HY-153609-5MG
1 mg
HY-153609-1MG
About this Product
- SKU:
- HY-153609
- Extra Details:
- AS-Patisiran sodium is an antisense strand of Patisiran. Patisiran is a double-stranded small interfering RNA that targets a sequence within the transthyretin (TTR) messenger RNA. Patisiran specifically inhibits hepatic synthesis of mutant and wild-type TTR. Patisiran can be used for the research of hereditary TTR amyloidosis[1][2][3].
- Molecular Weight:
- 6661.30
- Purity:
- 95.10
- References:
- [1]Adams D, et, al. Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis. N Engl J Med. 2018 Jul 5;379(1):11-21.|[2]Hoy SM. Patisiran: First Global Approval. Drugs. 2018 Oct;78(15):1625-1631.|[3]Kristen AV, et, al. Patisiran, an RNAi therapeutic for the treatment of hereditary transthyretin-mediated amyloidosis. Neurodegener Dis Manag. 2019 Feb;9(1):5-23.
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; sealed storage; away from moisture)
- Type:
- Molecular Biology Reagents: Nucleic Acids
- Pathway:
- Epigenetics;Neuronal Signaling
